#EXP00218

General

Accession	EXP00218
Activity	Formation (3-24h)
Date	2014-02-28
Administration	Coated
Model	in vivo

Organism	Pseudomonas aeruginosa ATCC 27853
Status	Validated
Notes	in a subcutaneous rat pouch model of infection/Stent-bonded peptide

Peptide

Tachyplesin III

KWCFRVCYRGICYRKCR

Experimental activity

Method	Concentration	Notes
Total countable CFUs	4.466 uM	No notes

References

The antimicrobial peptide Tachyplesin III coated alone and in combination with intraperitoneal piperacillin-tazobactam prevents ureteral stent Pseudomonas infection in a rat subcutaneous pouch model

Daniele Minardi, Roberto Ghiselli, Oscar Cirioni, Andrea Giacometti, Wojciech Kamysz, Fiorenza Orlando, Carmela Silvestri, Gianni Parri, Elzbieta Kamysz, Giorgio Scalise, Vittorio Saba, Muzzonigro Giovanni

2007. Peptides 12:2293-2298